Emeritus Faculty

Dale Bredesen, MD

Dr. Bredesen came to the Buck Institute in 1998 as its founding President and CEO. He is internationally recognized as an expert in the mechanisms of neurodegenerative diseases such as Alzheimer’s. His research has led to new insights that explain the erosion of memory seen in Alzheimer’s disease, and has opened the door to a new therapeutic approach. Dr. Bredesen earned his MD from Duke University Medical Center in Durham, NC.  He served as Chief Resident in Neurology at the University of California, San Francisco (UCSF) before joining Nobel laureate Stanley Prusiner’s laboratory at UCSF as an NIH Postdoctoral Fellow.  He has held faculty positions at UCSF, UCLA and the University of California, San Diego. 

David Greenberg, MD, PhD

Dr. Greenberg received MD and PhD (Pharmacology & Experimental Therapeutics) degrees from the Johns Hopkins University School of Medicine and clinical training in internal medicine at New York Hospital-Cornell University Medical Center and in neurology at the University of California, San Francisco (UCSF). He served on the faculty of the Department of Neurology at UCSF and the Departments of Neurology and Neurobiology at the University of Pittsburgh before joining the Buck Institute as Professor and Vice President for Special Research Programs in 1999. His research concerns mechanisms involved in stroke pathogenesis and repair, with emphasis on neuroprotective proteins (vascular endothelial growth factor, neuroglobin) and neurogenesis.

David G. Nicholls, PhD

David Nicholls has researched mitochondrial function for 50 years and has more than 300 publications. He is perhaps best known as the author (with Stuart Ferguson) of the standard textbook ‘Bioenergetics’, the 4th edition of which was published in 2013. He is known in addition for his discovery of the original uncoupling protein, UCP1, for work on mitochondrial calcium transport and isolated nerve terminals and for his research into mitochondrial dysfunction in nerve cells. Dr. Nicholls received his Ph.D., in Biochemistry from the University of Bristol, England. He is a Fellow of the Royal Society of Edinburgh and holder of the 2008 Mitchell Memorial Medal from the European Bioenergetics Congress. He established the bioenergetics core when he came to the Buck in 2000.

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